Forms and strengths
- Serums and moisturizers with sodium hyaluronate at various molecular weights
How to use it
On damp skin, then seal with a moisturizer. Works best under an occlusive in dry climates.
Side effects and cautions
- Rare irritation from preservatives or fragrance
- Tightness if used alone in dry air
Get advice first if
Compatible with pregnancy and all actives.
Regulatory status
Cosmetic ingredient; the injectable fillers are FDA-regulated medical devices.
In the trends
Skin flooding and 'seven-skin' layering routines are largely about this molecule.
Sources on file
These links support the claims above. Reviewed September 1, 2026. Drug labels link to DailyMed searches so the current label is always one click away.
- Dermatol Ther 2022 — topical hyaluronic acid for skin quality and aging: review and clinical evidence (PubMed) (opens in a new tab)
- Arch Dermatol Res 2024 — topical hyaluronic acid of different molecular weights in xerosis: double-blind RCT (PubMed) (opens in a new tab)
- American Academy of Dermatology — tips to relieve dry skin (opens in a new tab)