Forms and strengths

  • 0.75% gel, cream, and lotion (Rx, generic)
  • 1% gel and cream (Rx)

How to use it

Thin layer once or twice daily to affected areas; continue for maintenance once clear. Pair with gentle cleansing, sunscreen, and trigger management.

Side effects and cautions

  • Dryness
  • Stinging or burning
  • Watery eyes if applied near the eyes
Get advice first if

Generally considered acceptable in pregnancy for topical use; confirm with your clinician. Avoid contact with eyes.

Regulatory status

FDA-approved prescription drug for inflammatory rosacea lesions; prescription-only in most jurisdictions.

Sources on file

These links support the claims above. Reviewed September 1, 2026. Drug labels link to DailyMed searches so the current label is always one click away.

  1. NIH DailyMed — topical metronidazole labels (opens in a new tab)
  2. JAAD Int 2025 — minocycline, metronidazole, ivermectin, and azelaic acid in papulopustular rosacea: network meta-analysis (PubMed) (opens in a new tab)
  3. JAMA Dermatol 2026 — topical preparations for moderate to severe rosacea: network meta-analysis (PubMed) (opens in a new tab)
  4. American Academy of Dermatology — rosacea treatment (opens in a new tab)