Forms and strengths
- 1% gel, lotion, solution, and foam (Rx, generic)
- Fixed combinations with benzoyl peroxide, tretinoin, or both (Rx)
How to use it
Once or twice daily on affected areas, always with benzoyl peroxide (combined product or separate application). Reassess at 12 weeks and taper off when clear.
Side effects and cautions
- Dryness and peeling
- Stinging
- Rare diarrhea or colitis reported with topical use
Get advice first if
History of antibiotic-associated colitis is a reason to avoid. Long-term solo use breeds resistance that affects future treatment.
Regulatory status
FDA-approved prescription drug for acne; prescription-only in most jurisdictions.
Sources on file
These links support the claims above. Reviewed September 1, 2026. Drug labels link to DailyMed searches so the current label is always one click away.